AbMole｜Tremelimumab 曲美木单抗(CAS号：745013-59-6

Tremelimumab (Ticilimumab) 是一种完全人源化的单克隆抗体，对细胞毒性 T 淋巴细胞抗原 4 (CTLA-4) 具有特异性，可用于转移性黑色素瘤研究。

1.化学性质

CAS号：745013-59-6

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2.参考文献

[1] No authors listed. Tremelimumab

[2] Masatoshi Kudo. Hepatobiliary Surg Nutr. Durvalumab plus tremelimumab in unresectable hepatocellular carcinoma

[3] Do-Youn Oh, et al. Lancet Gastroenterol Hepatol. Gemcitabine and cisplatin plus durvalumab with or without tremelimumab in chemotherapy-naive patients with advanced biliary tract cancer: an open-label, single-centre, phase 2 study

[4] Robin Kate Kelley, et al. J Clin Oncol. Safety, Efficacy, and Pharmacodynamics of Tremelimumab Plus Durvalumab for Patients With Unresectable Hepatocellular Carcinoma: Randomized Expansion of a Phase I/II Study

[5] Jonathan W Goldman, et al. Lancet Oncol. Durvalumab, with or without tremelimumab, plus platinum-etoposide versus platinum-etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated results from a randomised, controlled, open-label, phase 3 trial